When a person is exposed to asbestos, he or she inhales tiny asbestos fibres which are suspended in the air. These fibres pass into the respiratory system and end up becoming lodged in the lungs. An accumulation of asbestos fibres in the lining of the lungs like this can cause nearby cells to deform and eventually leads to what is known as pleural mesothelioma. Accumulation of asbestos fibres in the peritoneum (lining of the abdomen) can lead to peritoneal mesothelioma and build up of fibres around the tissue of the heart can cause pericardial mesothelioma. Asbestos fibres reach these places over time or because they have been transported there by the lymphatic system.
Mesothelioma has a very large latency period (time between getting the cancer and feeling the symptoms of it). This period is usually between 30 – 50 years and so a person who bears mesothelioma is unlikely to know that they have got it. This is why mesothelioma is so hard to diagnose in its early stages because it shows no symptoms and the few symptoms that it does show such as wheezing and shortness of breath are typical of far more common diseases such as pneumonia. The likelihood of being cured depends largely on how early and how aggressively the cancer is treated. If it is treated when it has fully developed and matured then it is extremely difficult to cure.
In this way, those at risk are those who have worked amongst asbestos. Construction workers, asbestos manufacturers or those who have lived within a mile of an asbestos factory are the people who have the largest contact with asbestos. Those who are in contact with these people are also at risk because asbestos fibres can stick to clothes and hair. The majority of people who are discovering that they have mesothelioma are elderly men of about 60 – 70. This was the generation which worked with asbestos a lot without sufficient protection. Many of these men are now lodging multi million dollar lawsuits against the companies who exposed them to the dangers of asbestos.
Friday, December 4, 2009
Wednesday, December 2, 2009
The Biological Behavior of mesothelioma
The biological behavior of the mesotheliomas can be predicted by their gross look, those shape and structures .
solitary, discrete masses are generally benign, whereas those, which grow diffusely, are usually malignant. Mesothelioma is a tumor emerging from mesothelial lining of serous cavities, most often covering of lungs (the pleural cavity) , rarely, in coverings of abdomen (peritoneal cavity) and covering the heart (pericardial sac).
They are two types benign and malignant.
Mesothelioma – Benign or Solitary.Benign or solitary can also called by pleural fibroma. Exposures of asbestos play no role on the e etiology of benign mesothelioma. Entirely it consists of a solitary, circumscribed, small, firm mass and generally less than one inch in diameter. Dense fibrous tissues can be seen by cut the surface. The tumor is composed by predominantly of collage fibers and reticulin with interspersed fibroblasts. Unusual, mesothelial lined clefts are seen in the tumor. Benign mesothelioma causes tumor is associated with systemic syndrome of osteoarthropathy or hypoglycemia. Removal of the tumor is generally curative.
Mesothelioma – Malignant or diffuse.It is a highly malignant tumor with high mortality and it is rare. Usually after 20 to 40 years exposure to asbestos the tumor can be detected. Almost 90 percent of malignant mesotheliomas are asbestos related.
solitary, discrete masses are generally benign, whereas those, which grow diffusely, are usually malignant. Mesothelioma is a tumor emerging from mesothelial lining of serous cavities, most often covering of lungs (the pleural cavity) , rarely, in coverings of abdomen (peritoneal cavity) and covering the heart (pericardial sac).
They are two types benign and malignant.
Mesothelioma – Benign or Solitary.Benign or solitary can also called by pleural fibroma. Exposures of asbestos play no role on the e etiology of benign mesothelioma. Entirely it consists of a solitary, circumscribed, small, firm mass and generally less than one inch in diameter. Dense fibrous tissues can be seen by cut the surface. The tumor is composed by predominantly of collage fibers and reticulin with interspersed fibroblasts. Unusual, mesothelial lined clefts are seen in the tumor. Benign mesothelioma causes tumor is associated with systemic syndrome of osteoarthropathy or hypoglycemia. Removal of the tumor is generally curative.
Mesothelioma – Malignant or diffuse.It is a highly malignant tumor with high mortality and it is rare. Usually after 20 to 40 years exposure to asbestos the tumor can be detected. Almost 90 percent of malignant mesotheliomas are asbestos related.
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